I have gone over my memories for the past several days; I am not sure how to explain my thoughts. I struggle on a day–to-day basis. I forget simple things and have for quite some time. I know a lot of it could be due to absent-mindedness or that I am trying to multi-task, but recently I have been getting nervous. My aunt and dad both suffer from Alzheimer’s. My aunt has been battling this disease for a few years, and my dad just newly diagnosed. I have a good deal of health issues so I thought my forgetting could be related to any of those issues accompanied by the stress I am under. I have been diagnosed with three “migraine associated” brain lesions. I battle with depression and anxiety, and I can get sick as I am immune compromised. Due to the lack of remembering I had to go through some baseline testing at my doctor’s office, which I failed. In November I am scheduled for a ½ day of medical tests which includes full memory testing. I am scared, and I have a lot against me, but it has not stopped me yet. Semantic memory errors were one of the top memory issues I faced. I forgot work passwords, processes for certain things, the date for a meeting, taking out the trash for trash day, using the water when it was shut off for construction, and phone numbers. I also had trouble with episodic memories. I could not recall many details from my past. I also struggled with reading and retaining the information. The third area I struggled with was Prospective memory errors. I forgot what I was going to say to my co-workers and while I was walking down the hallway, I forgot what I was doing. I also had a few tips of the tongue memory issues. I forgot a couple of my co-worker’s names, and I got frustrated and forgot some words I was going to say. Semantic memory is where most of my memory errors occurred; and actually, the other three categories given were close to the same.
I would like to see experiments done on anxiety, forgetfulness, and also on Alzheimer’s. I was reading an article on Alzheimer’s and research is being done on a new enzyme that could be key in reversing memory. It is called Sp3. There is still a lot of work they need to do and more research that needs to be done but according to Medical News Today, doctors took tissue from people’s brains postpartum who died from this disease and found a link between different enzymes. The link is between HDAC2 and sp3. C Paddock states, ‘Our findings indicate that targeting the HDAC2-Sp3 complex could enhance cognitive function without affecting HDAC2 function in other processes.’ The team that is working to find a cure found a specific molecule that could help develop a drug that can stop sp3 from binding to HDAC2. This showed, that like other HDAC inhibitors, the molecule doesn’t interfere with cell proliferation. If this ends up being the answer that could help stop or slow down the advancement of Alzheimer’s, could we test individuals at younger ages? If it is known a person lacks or has a particular gene or enzyme, can children, young adults, middle age people obtained what they need somehow to prevent getting Alzheimer’s? Would this eventually affect the number of people who get this devastating disease? I hope that this enzyme is what scientists were looking for and that this discovery will change the advancement of Alzheimer’s. I would l the physicians to test those ideas. I would also like them to test an older person with the disease and see if their memory improved and become more clear.
I hope they find a cure for this disease that affects so many people. It is hard on the person with the illness and devastating for their family. I have witnessed this and hope that a cure is found soon.